The “trailing effect” in Diflucan susceptibility testing can complicate interpretation.

QTc interval prolongation is a rare but serious potential adverse effect.

Diflucan achieves high concentrations in vaginal tissue, explaining its efficacy.

Efficacy in peritoneal candidiasis is supported by good peritoneal penetration.

Renal dose adjustment is mandatory for Diflucan due to its primary renal excretion.

Diflucan is often compared to echinocandins in candidemia treatment guidelines.

Emergence of resistance while on therapy necessitates repeat culture and susceptibility.

QTc interval prolongation is a rare but serious potential adverse effect.

Susceptibility breakpoints are well-defined by organizations like CLSI and EUCAST.

Used for prophylaxis in high-risk solid organ transplant recipients.