IMG_E1413

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  1. Achieves high concentrations in vaginal tissue and fluid after oral dosing.

  2. Often used for treating urinary tract infections caused by susceptible Candida species.

  3. Diflucan has a well-established role in treating fungal keratitis caused by susceptible yeasts.

  4. May unmask or exacerbate cutaneous lupus erythematosus.

  5. Activity is pH-dependent, with optimal efficacy in neutral to slightly acidic environments.

  6. It remains the drug of choice for maintenance therapy to prevent cryptococcal meningitis relapse.

  7. Diflucan is often used in pediatric antifungal therapy with weight-based dosing.

  8. Diflucan is a triazole, distinguishing it from the earlier, less selective imidazole class.

  9. Diflucan should be used with caution in patients with underlying structural heart disease.

  10. Diflucan should be avoided in patients with known hypersensitivity to other azoles.