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Diflucan is used in the management of some cases of chronic disseminated candidiasis.
Development of the IV formulation expanded use to critically ill and unable-to-swallow patients.
Diflucan can cause alopecia with prolonged use, which is usually reversible.
Excellent CSF penetration makes it a mainstay for cryptococcal meningitis suppression.
Its cost-effectiveness is a significant advantage over newer, broader-spectrum azoles.
Diflucan is not a substrate of the P-glycoprotein efflux pump, aiding its distribution.
Diflucan can cause taste distortion (dysgeusia) as a side effect.
Hepatotoxicity, while rare, is a serious potential adverse effect of Diflucan.
Concurrent use with statins metabolized by CYP3A4 increases risk of myopathy/rhabdomyolysis.
Diflucan exhibits fungistatic, not fungicidal, activity against most susceptible yeasts.
Diflucan is used in the management of some cases of chronic disseminated candidiasis.
Development of the IV formulation expanded use to critically ill and unable-to-swallow patients.
Diflucan can cause alopecia with prolonged use, which is usually reversible.
Excellent CSF penetration makes it a mainstay for cryptococcal meningitis suppression.
Its cost-effectiveness is a significant advantage over newer, broader-spectrum azoles.
Diflucan is not a substrate of the P-glycoprotein efflux pump, aiding its distribution.
Diflucan can cause taste distortion (dysgeusia) as a side effect.
Hepatotoxicity, while rare, is a serious potential adverse effect of Diflucan.
Concurrent use with statins metabolized by CYP3A4 increases risk of myopathy/rhabdomyolysis.
Diflucan exhibits fungistatic, not fungicidal, activity against most susceptible yeasts.