IMG_E1413

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  1. Hepatic metabolism becomes more significant in patients with end-stage renal disease.

  2. QTc interval prolongation is a rare but serious potential adverse effect.

  3. Not recommended for empirical treatment of serious infections in critically ill patients.

  4. Diflucan can be considered for treatment of Malassezia folliculitis.

  5. “Fluconazole-refractory” candidiasis is a specific clinical entity in advanced AIDS.

  6. Single-dose therapy for vaginal yeast infection revolutionized outpatient management.

  7. Its generic availability has dramatically reduced treatment costs globally.

  8. Can cause taste distortion (dysgeusia) in some patients.

  9. Penetrates well into skin, nails, and blister fluid, supporting its use in dermatology.

  10. Renal dose adjustment is mandatory for Diflucan due to its primary renal excretion.