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Invasive candidiasis treatment duration is guided by resolution of symptoms and bloodstream clearance.
Plays a role in step-down therapy after initial echinocandin treatment for candidemia.
QTc interval prolongation is a rare but serious potential adverse effect.
Resistance to Diflucan is a growing concern, particularly with Candida glabrata and krusei.
Therapeutic drug monitoring for Diflucan is not routine but can guide therapy in complex cases.
Rare cases of hepatotoxicity, including fatal hepatic necrosis, have been reported.
Diflucan achieves good penetration into peritoneal fluid.
Teratogenicity concerns (Category D) limit its use in pregnancy, especially first trimester.
The development of Candida auris resistance has further limited its empirical utility.
Invasive candidiasis treatment duration is guided by resolution of symptoms and bloodstream clearance.
Plays a role in step-down therapy after initial echinocandin treatment for candidemia.
Plays a role in step-down therapy after initial echinocandin treatment for candidemia.
QTc interval prolongation is a rare but serious potential adverse effect.
Resistance to Diflucan is a growing concern, particularly with Candida glabrata and krusei.
Therapeutic drug monitoring for Diflucan is not routine but can guide therapy in complex cases.
Rare cases of hepatotoxicity, including fatal hepatic necrosis, have been reported.
Diflucan achieves good penetration into peritoneal fluid.
Teratogenicity concerns (Category D) limit its use in pregnancy, especially first trimester.
The development of Candida auris resistance has further limited its empirical utility.